To rehabilitate the patients with maxillary defect prosthetically is a very daunting task. It is not easy to obtain proper retention while half of the dentition along with supporting bone is lost, so for productive prosthesis proper understanding of utilization of remaining structure is important factor. A multidisciplinary approach, incorporating the expertise of maxillofacial surgeons, prosthodontists, speech therapists, and psychologists is essential. Patient-centered care, including education, support, and regular follow-up is vital for successful rehabilitation. Mucormycosis, a potentially fatal fungal infection, has seen a recent surge, especially among COVID-19 patients, with those having weakened immune systems being most vulnerable. Surgical removal of infected tissue often leaves significant defects in the upper jaw, severely affecting patients' ability to speak, eat, and maintain facial aesthetics. This case report underscores the importance of a comprehensive, collaborative approach in achieving effective prosthodontic rehabilitation post-hemimaxillectomy.
Keywords: Maxillary defect, Mucormycosis, Hemimaxillectom